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货号： bs-7154R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7154R-AF488
- 英文名称
- Anti-ZNF139/AF488
- 中文名称
- AF488标记的锌指蛋白139抗体
- 别 名
- 9130423L19Rik; KOX18; MGC138429; MGC63357; OTTHUMP00000210080; PHZ 37; PHZ-37; Zinc finger protein 139; Zinc finger protein 36 (KOX 18); Zinc finger protein 36; Zinc finger protein KOX18; Zinc finger protein with KRAB and SCAN domains 1; ZKSC1_HUMAN; ZKSCAN1; ZNF139; ZNF36.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 转录调节因子 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 64kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ZNF139
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The ZKSCAN1 gene encodes a transcriptional regulator of the KRAB (Kruppel-associated box) subfamily of zinc finger proteins, which contain repeated Cys2-His2 (C2H2) zinc finger domains that are connected by conserved sequences, called H/C links (summarized by Tommerup and Vissing, 1995 [PubMed 7557990]). Transcriptional regulatory proteins containing tandemly repeated zinc finger domains are thought to be involved in both normal and abnormal cellular proliferation and differentiation. See ZNF91 (MIM 603971) for general information on zinc finger proteins.[supplied by OMIM, Jul 2010]
Function:
May be involved in transcriptional regulation.
Subcellular Location:
Nucleus.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the krueppel C2H2-type zinc-finger protein family.
Contains 6 C2H2-type zinc fingers.
Contains 1 KRAB domain.
Contains 1 SCAN box domain.
Database links:Entrez Gene: 7586Human
Entrez Gene: 74570Mouse
Entrez Gene: 498160Rat
Omim: 601260Human
SwissProt: P17029Human
SwissProt: Q8BGS3Mouse
SwissProt: Q4KLI1Rat
Unigene: 615360Human
Unigene: 213114Mouse
Unigene: 113295Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.