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货号： bs-12717R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12717R-AF488
- 英文名称
- Anti-PLD3/AF488
- 中文名称
- AF488标记的胆碱磷酸酯酶3抗体
- 别 名
- Choline phosphatase 3; HindIII K4L homolog; HU K4; Hu-K4; HUK4; Phosphatidylcholine hydrolyzing phospholipase D3; Phosphatidylcholine-hydrolyzing phospholipase D3; Phospholipase D family, member 3; Phospholipase D3; PLD 3; PLD3; PLD3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 Alzheimers
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 55kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PLD3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the phospholipase D (PLD) family of enzymes that catalyze the hydrolysis of membrane phospholipids. The encoded protein is a single-pass type II membrane protein and contains two PLD phosphodiesterase domains. This protein influences processing of amyloid-beta precursor protein. Mutations in this gene are associated with Alzheimer disease risk. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Apr 2014]
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Widely expressed. Expressed at higher level in brain. Expressed at low level in corpus callosum, suggesting that it is highly expressed in neurons.
Post-translational modifications:
Glycosylated.
Similarity:
Belongs to the phospholipase D family.
Contains 2 PLD phosphodiesterase domains.
Database links:Entrez Gene: 23646Human
Entrez Gene: 18807Mouse
Entrez Gene: 361527Rat
SwissProt: Q2KJJ8Cow
SwissProt: Q8IV08Human
SwissProt: O35405Mouse
SwissProt: Q5FVH2Rat
Unigene: 257008Human
Unigene: 6483Mouse
Unigene: 128036Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.