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货号： bs-12692R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12692R-AF488
- 英文名称
- Anti-PKIB/AF488
- 中文名称
- AF488标记的蛋白激酶抑制蛋白β抗体
- 别 名
- cAMP dependent protein kinase inhibitor 2; cAMP-dependent protein kinase inhibitor beta; FLJ23817; IPKB_HUMAN; OTTHUMP00000017115; OTTHUMP00000017116; OTTHUMP00000017117; PKI-beta; PKIB; PRKACN2; Protein kinase (cAMP dependent, catalytic) inhibitor beta.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 8kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PKIB
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the cAMP-dependent protein kinase inhibitor family. The encoded protein may play a role in the protein kinase A (PKA) pathway by interacting with the catalytic subunit of PKA, and overexpression of this gene may play a role in prostate cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
Function:
Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.
Subcellular Location:
cytoplasm.
Similarity:
Belongs to the PKI family.
Database links:Entrez Gene: 5570Human
Entrez Gene: 18768Mouse
Omim: 606914Human
SwissProt: Q9C010Human
SwissProt: Q04758Mouse
Unigene: 726217Human
Unigene: 262135Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.