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货号： bs-19861R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19861R-AF488
- 英文名称
- Anti-RGS3/AF488
- 中文名称
- AF488标记的G蛋白信号转导调节因子3抗体
- 别 名
- C2PA; FLJ20370; FLJ31516; FLJ90496; PDZ RGS 3; PDZ RGS3; Regulator of G protein signaling 3; Regulator of G protein signalling 3; Regulator of G-protein signaling 3; RGP 3; RGP3; RGS 3; RGS3; RGS3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 132kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human RGS3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
Subcellular Location:
Cytoplasm. Nucleus. Cell membrane. Long isoforms are cytoplasmic and associated with the plasma membrane. Short isoforms are nuclear.
Post-translational modifications:
Phosphorylated by cyclic GMP-dependent protein kinase.ISGylated.
Similarity:
Contains 1 C2 domain.
Contains 1 PDZ (DHR) domain.
Contains 1 RGS domain.
Database links:Entrez Gene: 5998Human
Entrez Gene: 50780Mouse
Entrez Gene: 54293Rat
Omim: 602189Human
SwissProt: P49796Human
SwissProt: Q9DC04Mouse
SwissProt: P49797Rat
Unigene: 494875Human
Unigene: 286753Mouse
Unigene: 53900Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.