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货号： bs-19807R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19807R-AF488
- 英文名称
- Anti-SLC22A3/AF488
- 中文名称
- AF488标记的溶质载体家族蛋白22成员A3抗体
- 别 名
- EMT; EMT organic cation transporter 3; EMTH; Extraneuronal monoamine transporter; OCT 3; OCT3; Orct 3; Orct3; Organic cation transporter 3; S22A3_HUMAN; SLC22 A3; SLC22A 3; Slc22a3; Solute carrier family 22 (extraneuronal monoamine transporter) member 3; Solute carrier family 22 (organic cation transporter) member 3; Solute carrier family 22 member 3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 信号转导 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 61kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC22A3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. [provided by RefSeq, Jul 2008]
Function:
Mediates potential-dependent transport of a variety of organic cations. May play a significant role in the disposition of cationic neurotoxins and neurotransmitters in the brain.
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.
Similarity:
Belongs to the major facilitator superfamily. Organic cation transporter family.
Database links:Entrez Gene: 6581Human
Entrez Gene: 20519Mouse
Entrez Gene: 29504Rat
Omim: 604842Human
SwissProt: O75751Human
SwissProt: Q9WTW5Mouse
SwissProt: O88446Rat
Unigene: 567337Human
Unigene: 99252Mouse
Unigene: 24231Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.