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货号： bs-17402R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17402R-AF488
- 英文名称
- Anti-HSD17B13/AF488
- 中文名称
- AF488标记的17β羟基类固醇脱氢酶13/17β-HSD13抗体
- 别 名
- 17-beta-HSD 13; 17-beta-hydroxysteroid dehydrogenase 13; DHB13_HUMAN; HMFN0376; Hsd17b13; SCDR9; Short-chain dehydrogenase/reductase 9; UNQ497/PRO1014.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 新陈代谢 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human HSD17B13
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
17 beta-HSD13 (17 beta hydroxysteroid dehydrogenase type 13), also designated Short-chain dehydrogenase/reductase 9 (SCDR9), belongs to the 17 beta-HSD family of proteins, which regulate the availability of steroids within various tissues throughout the body. 17 beta-HSD13 is a 300 amino acid secreted protein that is highly expressed in liver and is also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis. The gene encoding 17 beta-HSD13 maps to chromosome 4, which houses nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntingtons disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
Function:
Highly expressed in the liver. Also detected in ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder and testis.
Subcellular Location:
Secreted.
Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
Database links:Entrez Gene: 345275Human
Entrez Gene: 243168Mouse
Entrez Gene: 305150Rat
Omim: 612127Human
SwissProt: Q7Z5P4 Human
SwissProt: Q8VCR2Mouse
SwissProt: Q5M875Rat
Unigene: 284414Human
Unigene: 284944Mouse
Unigene: 25104Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.