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货号： bs-17273R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17273R-AF488
- 英文名称
- Anti-SCARF2/AF488
- 中文名称
- AF488标记的清道夫受体F2抗体
- 别 名
- NSR1; Scarf2; Scavenger receptor class F member 2; Scavenger receptor expressed by endothelial cells 2 protein; SREC-II; SREC2; SREC2_HUMAN; SRECRP-1; SREPCR.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SCARF2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Function:
Probable adhesion protein, which mediates homophilic and heterophilic interactions. In contrast to SCARF1, it poorly mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL).
Subcellular Location:
Membrane.
Tissue Specificity:
Predominantly expressed in endothelial cells. Expressed in heart, placenta, lung, kidney, spleen, small intestine and ovary.
Similarity:
Contains 7 EGF-like domains.
Database links:Entrez Gene: 91179Human
Entrez Gene: 224024Mouse
Omim: 613619Human
SwissProt: Q96GP6Human
SwissProt: P59222Mouse
Unigene: 474251Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.