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货号： bs-17042R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-17042R-AF488
- 英文名称
- Anti-KIF18A/AF488
- 中文名称
- AF488标记的驱动蛋白家族成员18A抗体
- 别 名
- AU024633; B130001M12Rik; DKFZp434G2226; KI18A_HUMAN; KIF 18A; KIF18A; kinesin family member 18A; Kinesin like protein KIF18A; Kinesin-like protein KIF18A; Marrow stromal KIF18A; MGC27627; MS KIF18A; MS-KIF18A; RGD1561740; RP23 206C1.1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Chimpanzee,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 102kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human KIF18A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
KIF18A is a 898 amino acid protein that contains one kinesin-motor domain, which is responsible for the ATP-dependent movement of KIF18A across microtubules. KIF18A plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. Expression of KIF18A is induced by estrogen.
Function:
Microtubule-depolymerizing kinesin which plays a role in chromosome congression by reducing the amplitude of preanaphase oscillations and slowing poleward movement during anaphase, thus suppressing chromosome movements. May stabilize the CENPE-BUB1B complex at the kinetochores during early mitosis and maintains CENPE levels at kinetochores during chromosome congression.
Subcellular Location:
Cell projection > ruffle. Cytoplasm. Nucleus. Cytoplasm > cytoskeleton >centrosome.
Post-translational modifications:
Glycosylated.
Ubiquitinated.
Similarity:
Belongs to the kinesin-like protein family.
Contains 1 kinesin-motor domain.
Database links:Entrez Gene: 81930Human
Omim: 611271Human
SwissProt: Q8NI77Human
Unigene: 301052Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.