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货号： bs-16224R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16224R-AF488
- 英文名称
- Anti-GALNT9/AF488
- 中文名称
- AF488标记的GalNAc-T9蛋白抗体
- 别 名
- GalNAc T9; GalNAc transferase 9; GalNAc-T9; GALNT9; GALT9_HUMAN; Polypeptide GalNAc transferase 9; Polypeptide N acetylgalactosaminyltransferase 9; Polypeptide N-acetylgalactosaminyltransferase 9; pp GaNTase 9; pp-GaNTase 9; Protein UDP acetylgalactosaminyltransferase 9; Protein-UDP acetylgalactosaminyltransferase 9; UDP GalNAc polypeptide N acetylgalactosaminyltransferase 9; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 9; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9).
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 神经生物学 信号转导 新陈代谢
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Zebrafish, Sheep, Danio
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 68kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GALNT9
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. This gene is expressed specifically in the brain, with highest expression in the cerebellum. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function:
Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Does not glycosylate apomucin or SDC3.
Subcellular Location:
Golgi apparatus membrane.
Tissue Specificity:
Specifically expressed in brain. Not expressed in heart, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocyte. In brain, it is expressed in cerebellum, frontal lobe, temporal lobe, putamen and spinal cord, weakly expressed in cerebral cortex. Not expressed in medulla and occipital pole.
Similarity:
Belongs to the glycosyltransferase 2 family. GalNAc-T subfamily.
Contains 1 ricin B-type lectin domain.
Database links:Entrez Gene: 50614Human
Entrez Gene: 504951Cow
Entrez Gene: 486224Dog
Entrez Gene: 100718062 Guinea pig
Entrez Gene: 231605Mouse
Entrez Gene: 100156842Pig
Entrez Gene: 304571Rat
Entrez Gene: 797549Zebrafish
Omim: 606251Human
SwissProt: Q9HCQ5Human
Unigene: 301062Human
Unigene: 658249Human
Unigene: 275748Mouse
Unigene: 105079Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.