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货号： bs-16110R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-16110R-AF488
- 英文名称
- Anti-FLJ20530/C8orf52/AF488
- 中文名称
- AF488标记的8号染色体开放阅读框52抗体
- 别 名
- C8orf52; Chromosome 8 open reading frame 52; FLJ20530; INT8; Integrator complex subunit 8; INTS 8; INT8_HUMAN ； INTS8; KAONASHI protein 1; KAONASHI1; MGC131633.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 113kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human FLJ20530/C8orf52
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a subunit of the Integrator complex which is involved in the cleavage of small nuclear RNAs U1 and U2 within the nucleus. The encoded protein associates with RNA polymerase II and is recruited to the U1 and U2 small nuclear RNA genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Function:
FLJ20530 is a component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3 box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
Subunit:
Belongs to the multiprotein complex Integrator, at least composed of INTS1, INTS2, INTS3, INTS4, INTS5, INTS6, INTS7, INTS8, INTS9/RC74, INTS10, CPSF3L/INTS11 and INTS12.
Subcellular Location:
Nuclear
Similarity:
Contains 4 TPR repeats.
Database links:Entrez Gene: 55656Human
Entrez Gene: 72656Mouse
Omim: 611351Human
SwissProt: Q75QN2Human
SwissProt: Q80V86Mouse
Unigene: 521693Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.