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货号： bs-14041R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-14041R-AF488
- 英文名称
- Anti-CR16/AF488
- 中文名称
- AF488标记的糖皮质激素区域表达蛋白16抗体
- 别 名
- Corticosteroids and regional expression protein 16 homolog; WAS/WASL-interacting protein family member 3; Wipf3; WIPF3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Horse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 49kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CR16
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
CR16 is a 483 amino acid proline-rich cytoplasmic protein that is thought to regulate cytoskeletal organization. A member of both the verprolin and Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP) families, CR16 colocalizes with N-WASP (Neuronal Wiskott-Aldrich syndrome protein) in tips of growth cone filopodia, primary hippocampal neurons and Sertoli cell-spermatid junctions. CR16 and N-WASP functionally interact to influence spermatogenesis. CR16 is predominantly expressed in brain and testis, contains one WH2 domain, a KLKR motif, three profilin-binding motifs and is encoded by a gene that maps to human chromosome 7p15.1.
Function:
May be a regulator of cytoskeletal organization. May have a role in spermatogenesis.
Subcellular Location:
Cytoplasm. In hippocampal neurons colocalizes with WASL in the cell body, axons and the growth cone.
Similarity:
Belongs to the verprolin family.
Contains 1 WH2 domain.
Database links:Entrez Gene: 644150Human
SwissProt: A6NGB9Human
Unigene: 709280Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.