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货号： bs-9202R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9202R-AF488
- 英文名称
- Anti-IGSF12/AF488
- 中文名称
- AF488标记的免疫球蛋白超家族成员12抗体
- 别 名
- IGSF12; CD300 antigen-like family member A; CD300a; CD300a molecule; CLM-8; CLM8_HUMAN; CMRF 35 H9; CMRF-35-H9; CMRF35-H; CMRF35-H9; CMRF35-like molecule 8; CMRF35H leukocyte immunoglobulin like receptor; CMRF35H9; IgSF12; Immunoglobulin superfamily member 12; Inhibitory receptor protein 60; IRC1; IRC1/IRC2; IRC2; IRp60; Leukocyte membrane antigen; Mast cell derived paired immunoglobulin like receptor 1; NK inhibitory receptor; Polymeric immunoglobulin receptor 4.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 免疫学 细胞类型标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 31kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human IGSF12/CD300
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
Function:
Inhibitory receptor which may contribute to the down-regulation of cytolytic activity in natural killer (NK) cells, and to the down-regulation of mast cell degranulation.
Subunit:
Upon tyrosine-phosphorylation, interacts with PTN6/SHP-1 and PTPN11/SHP-2 and INPP5D.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein (Potential).
Tissue Specificity:
Expressed not only by natural killer (NK) cells but also by T-cell subsets, B-cells, dendritic cells, mast cells, granulocytes and monocytes.
Post-translational modifications:
Phosphorylated on tyrosine.
Similarity:
Belongs to the CD300 family.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
Database links:Entrez Gene: 11314 Human
Omim: 606790 Human
SwissProt: Q9UGN4 Human
Unigene: 9688 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.