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货号： bs-9236R-AF488 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9236R-AF488
- 英文名称
- Anti-CDX2+3/AF488
- 中文名称
- AF488标记的尾侧型同源转录因子2/3抗体
- 别 名
- Caudal type homeo box 2; Caudal type homeo box transcription factor 2; Caudal type homeobox 2; Caudal type homeobox protein 2; caudal type homeobox transcription factor 2; Caudal-type homeobox protein 2; CDX 2; CDX 3; CDX-3; Cdx2; CDX2_HUMAN; CDX3; CDX2+3; Homeobox protein CDX 2; Homeobox protein CDX-2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 发育生物学 信号转导 干细胞 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Pig, Cow, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 34kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human CDX2/3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded protein is a major regulator of intestine-specific genes involved in cell growth an differentiation. This protein also plays a role in early embryonic development of the intestinal tract. Aberrant expression of this gene is associated with intestinal inflammation and tumorigenesis. [provided by RefSeq, Jan 2012].
Function:
Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.
Subcellular Location:
Nucleus.
Post-translational modifications:
Phosphorylation of Ser-60 mediates the transactivation capacity.
Similarity:
Belongs to the Caudal homeobox family.
Contains 1 homeobox DNA-binding domain.
Database links:Entrez Gene: 1045 Human
Entrez Gene: 12591 Mouse
Entrez Gene: 66019 Rat
Omim: 600297 Human
SwissProt: Q99626 Human
SwissProt: P43241 Mouse
Unigene: 174249 Human
Unigene: 20358 Mouse
Unigene: 64495 Ra
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.