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货号： bsm-51333M-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-51333M-AF350
- 英文名称
- Anti-RAB18/AF350
- 中文名称
- AF350标记的小鼠抗G蛋白家族RAB18蛋白单克隆抗体
- 别 名
- RAB18; RAB18 member RAS oncogene family; RAB18 small GTPase; RAB18_HUMAN; RAB18LI1; Ras-related protein Rab-18.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导 转录调节因子 G蛋白信号
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 3A8
- 交叉反应
- Human, Mouse, Rat,
- 产品应用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 23kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- Recombinant human RAB18 protein
- 亚 型
- IgG1
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a member of a family of Ras-related small GTPases that regulate membrane trafficking in organelles and transport vesicles. Knockdown studies is zebrafish suggest that this protein may have a role in eye and brain development. Mutations in this gene are associated with Warburg micro syndrome type 3. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Function:
Plays a role in apical endocytosis/recycling. May be implicated in transport between the plasma membrane and early endosomes. Plays a key role in eye and brain development and neurodegeneration.
Subcellular Location:
Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Specificity:
Ubiquitous.
Similarity:
Belongs to the small GTPase superfamily. Rab family.
Database links:Entrez Gene: 22931 Human
Entrez Gene: 19330 Mouse
Entrez Gene: 307039 Rat
Omim: 602207 Human
SwissProt: Q9NP72 Human
SwissProt: P35293 Mouse
SwissProt: Q5EB77 Rat
Unigene: 406799 Human
Unigene: 132802 Mouse
Unigene: 472772 Mouse
Unigene: 53248 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.