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货号： bsm-33243M-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-33243M-AF350
- 英文名称
- Anti-Transferrin/AF350
- 中文名称
- AF350标记的转铁蛋白单克隆抗体
- 别 名
- Apotransferrin; Beta 1 metal binding globulin; DKFZp781D0156; PRO1400; PRO1557; PRO2086; Serotransferrin precursor; Siderophilin; TF; Transferin; Transferrin; TRFE_HUMAN; Beta-1 metal-binding globulin; Serotransferrin.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 克 隆 号
- 12A7
- 交叉反应
- Human,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 77kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- Full length native Transferrin protein purified from human plasma
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a glycoprotein with an approximate molecular weight of 76.5 kDa. It is thought to have been created as a result of an ancient gene duplication event that led to generation of homologous C and N-terminal domains each of which binds one ion of ferric iron. The function of this protein is to transport iron from the intestine, reticuloendothelial system, and liver parenchymal cells to all proliferating cells in the body. This protein may also have a physiologic role as granulocyte/pollen-binding protein (GPBP) involved in the removal of certain organic matter and allergens from serum. [provided by RefSeq, Sep 2009].
Function:
Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.
Subunit:
Monomer.
Subcellular Location:
Secreted.
Tissue Specificity:
Expressed by the liver and secreted in plasma.
DISEASE:
Defects in TF are the cause of atransferrinemia (ATRAF) [MIM:209300]. Atransferrinemia is rare autosomal recessive disorder characterized by iron overload and hypochromic anemia.
Similarity:
Belongs to the transferrin family.
Contains 2 transferrin-like domains.
Database links:Entrez Gene: 7018 Human
Entrez Gene: 22041 Mouse
Entrez Gene: 24825 Rat
Omim: 190000 Human
SwissProt: P02787 Human
SwissProt: Q921I1 Mouse
SwissProt: P12346 Rat
Unigene: 518267 Human
Unigene: 37214 Mouse
Unigene: 91296 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.