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货号： bs-4401R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4401R-AF350
- 英文名称
- Anti-NUDT15/AF350
- 中文名称
- AF350标记的NUDT15蛋白抗体
- 别 名
- 8-dihydro-8-oxoguanine triphosphatase NUDT15; 8-oxo-dGTPase NUDT15; A730068G11Rik; EC 3.1.6.-; FLJ10956; MGC104352; MTH2; MutT homolog 2; Nucleoside diphosphate-linked moiety X motif 15; NUD15_HUMAN; Nudix (nucleoside diphosphate linked moiety X)-type motif; Nudix motif 15; NUDT15; OTTHUMP00000018389; Probable 7; Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15; RP11-90M2.1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 19kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NUDT15
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- Function:
Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
Similarity:
Belongs to the Nudix hydrolase family.
Contains 1 nudix hydrolase domain.
Database links:Entrez Gene: 55270Human
Entrez Gene: 214254Mouse
Entrez Gene: 290365Rat
SwissProt: Q9NV35Human
SwissProt: Q8BG93Mouse
Unigene: 144407Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.