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货号： bs-12780R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12780R-AF350
- 英文名称
- Anti-VRK2/AF350
- 中文名称
- AF350标记的丝氨酸/苏氨酸蛋白激酶vrk2抗体
- 别 名
- 2810003O05Rik; AI447698; EC 2.7.11.1; Serine/threonine protein kinase VRK2; Serine/threonine-protein kinase VRK2; Vaccinia related kinase 2; Vaccinia virus B1R related kinase 2; Vaccinia-related kinase 2; VRK 2; VRK2; VRK2_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 细胞凋亡 转录调节因子 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 58kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human VRK2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in this gene have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity. [provided by RefSeq, Jan 2014]
Function:
Probable serine/threonine kinase.
Subcellular Location:
Membrane.
Tissue Specificity:
Widely expressed. Highly expressed in fetal liver, skeletal muscle, pancreas, heart, peripheral blood leukocytes and testis.
Similarity:
Belongs to the protein kinase superfamily.
CK1 Ser/Thr protein kinase family.
VRK subfamily.
Contains 1 protein kinase domain.
Database links:Entrez Gene: 7444Human
Entrez Gene: 69922Mouse
Omim: 602169Human
SwissProt: Q86Y07Human
SwissProt: Q8BN21Mouse
Unigene: 728198Human
Unigene: 285351Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.