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货号： bs-12684R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12684R-AF350
- 英文名称
- Anti-TPSG1/AF350
- 中文名称
- AF350标记的膜类胰蛋白酶1抗体
- 别 名
- gamma I; gamma II; lung tryptase; mast cell protease II; mast cell tryptase; pituitary tryptase; PRSS31; Serine protease 31; skin tryptase; TMT; Tpsg1; Transmembrane tryptase; trpA; TRYG1_HUMAN; Tryptase gamma (EC:3.4.21.-); tryptase gamma 1; tryptase gamma; Tryptase gamma heavy chain; tryptase gamma I; tryptase gamma II; Tryptase gamma light chain.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 泛素 细胞膜蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 32kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TPSG1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Tryptases comprise a family of trypsin-like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. There is uncertainty regarding the number of genes in this cluster. Currently four functional genes - alpha I, beta I, beta II and gamma I - have been identified. And beta I has an allelic variant named alpha II, beta II has an allelic variant beta III, also gamma I has an allelic variant gamma II. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha-tryptases predominant. This gene differs from other members of the tryptase gene family in that it has C-terminal hydrophobic domain, which may serve as a membrane anchor. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders. [provided by RefSeq, Jul 2008]
Subcellular Location:
Membrane.
Tissue Specificity:
Expressed in many tissues.
Similarity:
Belongs to the peptidase S1 family.
Tryptase subfamily.
Contains 1 peptidase S1 domain.
Database links:Entrez Gene: 25823Human
Entrez Gene: 26945Mouse
Entrez Gene: 302990Rat
Omim: 609341Human
SwissProt: Q9NRR2Human
SwissProt: Q9QUL7Mouse
Unigene: 592076Human
Unigene: 180108Mouse
Unigene: 163109Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.