产品中心
当前位置：首页>产品中心Anti-PRCC/Papillary renal cell carcinoma/AF350
货号： bs-21077R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21077R-AF350
- 英文名称
- Anti-PRCC/Papillary renal cell carcinoma/AF350
- 中文名称
- AF350标记的头状肾细胞癌PRCC抗体
- 别 名
- Papillary renal cell carcinoma (Translocation associated), isoform CRA_b; Papillary renal cell carcinoma translocation-associated gene protein; PRCC; PRCC_HUMAN; Proline rich protein PRCC; Proline-rich protein PRCC; RCCP1; TPRC.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PRCC/Papillary renal cell carcinoma
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein that may play a role in pre-mRNA splicing. Chromosomal translocations (X;1)(p11;q21) that result in fusion of this gene to TFE3 (GeneID 7030) have been associated with papillary renal cell carcinoma. A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation. This fusion protein has also been associated with disruption of the cell cycle.[provided by RefSeq, Aug 2010]
Function:
May regulate cell cycle progression through interaction with MAD2L2.
Subunit:
Interacts with MAD2L2; the interaction is direct.
Subcellular Location:
Nucleus.
Tissue Specificity:
Ubiquitous in fetal and adult tissues.
DISEASE:
Note=A chromosomal aberration involving PRCC is found in patients with papillary renal cell carcinoma. Translocation t(X;1)(p11.2;q21.2) with TFE3.
Database links:Entrez Gene: 5546Human
Entrez Gene: 94315Mouse
Omim: 179755Human
SwissProt: Q92733Human
Unigene: 516948Human
Unigene: 35089Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.