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货号： bs-21038R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-21038R-AF350
- 英文名称
- Anti-ROD1/PTBP3/AF350
- 中文名称
- AF350标记的调节分化蛋白ROD1抗体
- 别 名
- DKFZp781I1117; Fission yeast differentiation regulator; OTTHUMP00000021931; OTTHUMP00000021932; Polypyrimidine tract binding protein 3; regulator of differentiation 1; Regulator of differentiation (in S. pombe) 1; Regulator of differentiation 1; ROD 1; Rod1; ROD1 regulator of differentiation 1; ROD1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 结合蛋白 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, Sheep, Danio
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ROD1/PTBP3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene binds RNA and is a regulator of cell differentiation. The encoded protein preferentially binds to poly(G) and poly(U) sequences in vitro. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Function:
RNA-binding protein that mediates pre-mRNA alternative splicing regulation. Plays a role in the regulation of cell proliferation, differentiation and migration. Positive regulator of EPO-dependent erythropoiesis. Participates in cell differentiation regulation by repressing tissue-specific exons. Promotes FAS exon 6 skipping. Binds RNA, preferentially to both poly(G) and poly(U).
Subcellular Location:
Contains 4 RRM (RNA recognition motif) domains.
Tissue Specificity:
Expressed in several hematopoietic cell lines examined.
Similarity:
Contains 4 RRM (RNA recognition motif) domains.
Database links:Entrez Gene: 9991Human
Entrez Gene: 230257Mouse
Entrez Gene: 83515Rat
Omim: 607527Human
SwissProt: O95758Human
SwissProt: Q8BHD7Mouse
SwissProt: Q9Z118Rat
Unigene: 269988Human
Unigene: 331640Mouse
Unigene: 162818Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.