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货号： bs-19963R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19963R-AF350
- 英文名称
- Anti-PRKRIR/AF350
- 中文名称
- AF350标记的蛋白激酶PKR抑制蛋白PRKRIR抗体
- 别 名
- 52 kDa repressor of the inhibitor of the protein kinase; 58 kDa interferon induced protein kinase interacting protein; DAP4; Death associated protein 4; Inhibitor of protein kinase PKR; Interferon inducible double stranded RNA dependent inhibitor; MGC102750; P52rIPK; P58 repressor; p58IPK interacting protein; THAP domain containing protein 0; THAP0.P52K_HUMAN
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 激酶和磷酸酶
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 88kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human PRKRIR
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
PRKRIR is upstream regulator of interferon induced serine/threonine protein kinase R (PKR). It may block the PKR inhibitory function of P58IPK, resulting in the restoration of kinase activity and suppression of cell growth.
Function:
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR). May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
Subunit:
Interacts with P58IPK, probably sequestring it.
Subcellular Location:
Nucleus
Similarity:
Contains 1 THAP-type zinc finger.
Database links:Entrez Gene: 5612Human
Entrez Gene: 72981Mouse
Entrez Gene: 308845Rat
Omim: 607374Human
SwissProt: O43422Human
SwissProt: Q9CUX1Mouse
SwissProt: Q9R0T3Rat
Unigene: 503315Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.