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货号： bs-19829R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-19829R-AF350
- 英文名称
- Anti-SLC39A14/AF350
- 中文名称
- AF350标记的溶质载体家族蛋白39成员A14抗体
- 别 名
- Cig19; KIAA0062; LIV-1 subfamily of ZIP zinc transporter 4; LZT-Hs4; NET34; S39AE_HUMAN; SLC39A14; Solute carrier family 39 (zinc transporter), member 14; Solute carrier family 39 member 14; Zinc transporter ZIP14; ZIP-14; ZIP14; Zrt Irt like protein 14; Zrt- and Irt-like protein 14.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 发育生物学 信号转导 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Chimpanzee,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 51kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SLC39A14
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]
Function:
May be able to transport iron (By similarity). Acts as a zinc-influx transporter.
Subunit:
Homotrimer.
Subcellular Location:
Cell membrane. Cell projection > lamellipodium. Localized to the plasma membrane and also found colocalized with F-actin concentrated on lamellipodiae.
Tissue Specificity:
Ubiquitously expressed, with increased expression in liver, pancreas, fetal liver, thyroid gland, left and right ventricle, right atrium and fetal heart. Weakly expressed in spleen, thymus, and peripheral blood leukocytes.
Similarity:
Belongs to the ZIP transporter (TC 2.A.5) family.
Database links:Entrez Gene: 464044Chimpanzee
Entrez Gene: 23516Human
Entrez Gene: 100387296 Marmoset (common)
Entrez Gene: 213053Mouse
Entrez Gene: 100172692Orangutan
Omim: 608736Human
SwissProt: Q15043Human
SwissProt: Q75N73Mouse
SwissProt: Q5RAB7Orangutan
Unigene: 491232Human
Unigene: 270647Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.