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货号： bs-12377R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-12377R
- 英文名称
- OSR1 + OSR2
- 中文名称
- OSR1/OSR2蛋白抗体
- 别 名
- FLJ90037; Odd skipped related 2; Odd skipped related 2A protein; Odd-skipped related; odd-skipped related 2 (Drosophila); Osr2; OSR2_HUMAN; Protein odd-skipped-related 2; ODD; Odd skipped Drosophila homolog; Odd skipped homolog; Odd skipped related 1 (Drosophila); Odd skipped related 1; Odd skipped related 1 Drosophila; Odd1; Protein odd skipped related 1; OSR1_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 细胞生物 发育生物学 干细胞 锌指蛋白 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, Danio rerio
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human OSR2 and OSR1:181-280/312
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
OSR2 is a 312 amino acid protein that contains five zinc finger domains. It is expressed in the kidneys, skeletal muscle, testis, and mouse embryos and may be involved in transcriptional activity and osteoblast function. The expression of OSR2 is regulated by C/EBP regulatory elements. OSR2 plays a role in regulating palatal development and expression of alkaline phosphatase. Two isoforms, OSR2A and OSR2B, are produced due to alternative splicing. OSR2B is 36 amino acids shorter than OSR2A and contains only three zinc finger motifs. Both isoforms localize to the nucleus and are thought to exhibit opposite transcriptional activities. Mutations in the gene encoding OSR2 can alter the gene expression of Pax-9 and TGF beta3.
Subcellular Location:
Nucleus.
Similarity:
Belongs to the Odd C2H2-type zinc-finger protein family.
Contains 5 C2H2-type zinc fingers.
SWISS:
Q8TAX0
Q8N2R0
Gene ID:
130497
116039
Database links:Entrez Gene: 539430 Cow
Entrez Gene: 130497 Human
Entrez Gene: 23967 Mouse
Entrez Gene: 298878 Rat
Omim: 608891 Human
SwissProt: Q08DS3 Cow
SwissProt: Q8TAX0 Human
SwissProt: Q9WVG7 Mouse
SwissProt: B0K011 Rat
Entrez Gene: 116039 Human
Entrez Gene: 107587 Mouse
Entrez Gene: 315039 Rat
Omim: 611297 Human
SwissProt: Q8N2R0 Human
SwissProt: Q91ZD1 Mouse
SwissProt: Q6AY34 Rat
Unigene: 253247 Human
Unigene: 46336 Mouse
Unigene: 13228 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Paraformaldehyde-fixed, paraffin embedded (Rat kidney); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (OSR1 + OSR2) Polyclonal Antibody, Unconjugated (bs-12377R) at 1:500 overnight at 4°C, followed by a conjugated secondary (sp-0023) for 20 minutes and DAB staining.
Tissue/cell: mouse embryo tissue ; 4% Paraformaldehyde-fixed and paraffin-embedded;
Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
Incubation: Anti-OSR2 Polyclonal Antibody, Unconjugated(bs-12377R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining