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货号： bs-12164R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12164R-AF350
- 英文名称
- Anti-Calneuron 1/AF350
- 中文名称
- AF350标记的钙营养蛋白1/钙结合蛋白8抗体
- 别 名
- CaBP8; CABP8_HUMAN; Calcium binding protein 8; Calcium binding protein; Calcium binding protein CABP8; Calcium-binding protein 8; Caln1; Calneuron I; Calneuron-1; Calneuron1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学 信号转导 结合蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 25kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Calneuron 1/CABP8
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a protein with high similarity to the calcium-binding proteins of the calmodulin family. The encoded protein contains two EF-hand domains and potential calcium-binding sites. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
Function:
Negatively regulates Golgi-to-plasma membranetrafficking by interacting with PI4KB and inhibiting its activity(By similarity). May play a role in the physiology of neurons andis potentially important in memory and learning.
Subunit:
Interacts with PI4KB. This binding competes withFREQ/NCS1 binding in a calcium-dependent manner.
Subcellular Location:
Golgi apparatus, trans-Golgi network membrane. Cytoplasm, perinuclear region. Cell membrane.
Tissue Specificity:
Brain specific.
Similarity:
Contains 2 EF-hand domains.
Database links:Entrez Gene: 83698Human
Entrez Gene: 140904Mouse
Entrez Gene: 363909Rat
Omim: 607176Human
SwissProt: Q9BXU9Human
SwissProt: Q9JJG7Mouse
SwissProt: Q06BI3Rat
Unigene: 592750Human
Unigene: 320206Mouse
Unigene: 202895Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.