产品中心
当前位置：首页>产品中心Anti-NAV3/AF350
货号： bs-12151R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12151R-AF350
- 英文名称
- Anti-NAV3/AF350
- 中文名称
- AF350标记的神经元引导蛋白3抗体
- 别 名
- KIAA0938; NAV 3; NAV3; NAV3_HUMAN; Neuron navigator 3; POMFIL1; Pore membrane and/or filament-interacting-like protein 1; Steerin 3; Steerin-3; STEERIN3; Unc 53 homolog 3; Unc-53 homolog 3; unc53H3.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 神经生物学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 255kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NAV3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.
Function:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.
Subcellular Location:
Nucleus outer membrane.
Tissue Specificity:
Highly expressed in brain. Expressed at low levels in heart and placenta. Present in activated T-cells but not in resting T-cells (at protein level). Down-regulated in primary neuroblastoma.
DISEASE:
Note=A chromosomal aberration disrupting NAV3 has been found in patients with Sezary syndrome. Translocation t(12;18)(q21;q21.2).
Similarity:
Sequence similarities; Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.
Database links:Entrez Gene: 89795 Human
Entrez Gene: 260315 Mouse
Entrez Gene: 314814 Rat
Omim: 611629 Human
SwissProt: Q8IVL0 Human
SwissProt: Q80TN7 Mouse
Unigene: 655301 Human
Unigene: 225050 Mouse
Unigene: 394160 Mouse
Unigene: 461280 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.