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货号： bs-12129R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12129R-AF350
- 英文名称
- Anti-ACCN4/AF350
- 中文名称
- AF350标记的脑钠通道蛋白4抗体
- 别 名
- Accn4; ACCN4_HUMAN; Acid sensing (proton gated) ion channel family member 4; Acid sensing ion channel 4; Acid-sensing ion channel 4; Amiloride sensitive cation channel 4; Amiloride sensitive cation channel 4 pituitary; Amiloride sensitive cation channel family member 4 pituitary; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4; ASIC4; BNAC4; Brain sodium channel 4; pituitary.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 通道蛋白 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 70kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ACCN4/ASIC4
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. [provided by RefSeq, Feb 2012].
Function:
Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity.
Subunit:
Homotrimer or heterotrimer with other ASIC proteins.
Subcellular Location:
.Membrane; Multi-pass membrane protein.
Tissue Specificity:
Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti.
Similarity:
Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. ACCN4 subfamily.
Database links:Entrez Gene: 55515 Human
Entrez Gene: 241118 Mouse
Entrez Gene: 63882 Rat
Omim: 606715 Human
SwissProt: Q96FT7 Human
SwissProt: Q7TNS7 Mouse
SwissProt: Q9JHS6 Rat
Unigene: 87469 Human
Unigene: 110790 Mouse
Unigene: 44831 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.