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货号： bs-12115R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12115R-AF350
- 英文名称
- Anti-DNER/AF350
- 中文名称
- AF350标记的脑表皮生长因子跨膜蛋白DNER抗体
- 别 名
- Brain EGF repeat-containing transmembrane protein; Bret; Delta and Notch-like epidermal growth factor-related receptor; Delta/notch-like EGF-related receptor; Dner; DNER_HUMAN; PRO299; Transmembrane protein Bet; UNQ26.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 信号转导 干细胞 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 75kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DNER
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
Function:
Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis.
Subunit:
Interacts with AP1G1. Interacts with NOTCH1.
Subcellular Location:
Cell membrane. Present on the membrane of dendrites and cell bodies but excluded from axonal membrane. Also found in early endosomes in the somatodendritic region.
Tissue Specificity:
Expressed in brain, spinal cord and adrenal gland.
Similarity:
Contains 10 EGF-like domains.
Contains 1 follistatin-like domain.
Database links:Entrez Gene: 92737 Human
Entrez Gene: 227325 Mouse
Entrez Gene: 316573 Rat
Omim: 607299 Human
SwissProt: Q8NFT8 Human
SwissProt: Q8JZM4 Mouse
Unigene: 234074 Human
Unigene: 292560 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.