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货号： bs-12024R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-12024R-AF350
- 英文名称
- Anti-GPR136/AF350
- 中文名称
- AF350标记的G蛋白偶联受体136抗体
- 别 名
- G protein-coupled receptor 136; G-protein coupled receptor PGR12; Gpr136; HGNC:21318; Neuropsin; OPN5; Opsin 5; PGR12; TMEM13; Transmembrane protein 13; OPN5_HUMAN; GPCR GPR136.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 40kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human G protein-coupled receptor 136
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
GPCR GPR136, also known as Opsin 5, is a member of the guanine nucleotide binding protein (G protein) coupled receptor superfamily. This gene belongs to the seven exon subfamily of mammalian opsin genes that includes peropsin (RRH) and retinal G protein coupled receptor (RGR). Like these other seven exon opsin genes, this gene may encode a protein with photoisomerase activity. Alternative splicing results in multiple transcript variants encoding different isoforms. ESTs for the GPR136 gene have been identified from human normal testis and B cell/lung/testis libraries..
Subcellular Location:
Membrane; Multipass membrane protein.
Tissue Specificity:
Detected in brain and retina and cell lines derived from neural retina.
Post-translational modifications:
It is uncertain whether Cys-315 or Cys-316 is palmitoylated.
Similarity:
Belongs to the G-protein coupled receptor 1 family. Opsin subfamily.
Database links:Entrez Gene: 221391Human
Entrez Gene: 353344Mouse
Entrez Gene: 316259Rat
SwissProt: Q6U736Human
SwissProt: Q6VZZ7Mouse
SwissProt: Q7TQN6Rat
Unigene: 213717Human
Unigene: 184937Mouse
Unigene: 97222Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.