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货号： bs-4200R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4200R-AF350
- 英文名称
- Anti-Selenium Binding Protein 1/AF350
- 中文名称
- AF350标记的硒结合蛋白1抗体
- 别 名
- 56 kDa selenium binding protein; 56 kDa selenium-binding protein; hSBP; LPSB; SBP; SBP1; SBP1_HUMAN; SBP56; Selenbp1; Selenbp2; Selenium binding protein 2; Selenium binding protein1; Selenium-binding protein 1; SELNBP1; SP56.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 免疫学 神经生物学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 52kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SBP1/Selenium Binding Protein 1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Selenium is an essential trace element that confers tolerance to toxicity arising through exposure to heavy metals or other reactive xenobiotics. Selenium exhibits potent anticarcinogenic properties, and deficiency of selenium may cause certain neurologic diseases. Both effects are attributed to selenium-binding proteins. Selenium binding protein 1 is down-regulated in lung adenocarcinoma, colorectal cander and ovarian cancer. It is two-fold upregulated in the brains of patients suffering from schizophrenia, and is therefore a biomarker for this disease.
Function:
Selenium-binding protein which may be involved in the sensing of reactive xenobiotics in the cytoplasm. May be involved in intra-Golgi protein transport.
Subunit:
Interacts with USP33.
Subcellular Location:
Nucleus. Cytoplasm, cytosol. Membrane; Peripheral membrane protein. Note=May associate with Golgi membrane. May associate with the membrane of autophagosomes.
Tissue Specificity:
Present in liver and colon (at protein level).
Post-translational modifications:
The N-terminus is blocked.
Similarity:
Belongs to the selenium-binding protein family.
Database links:Entrez Gene: 8991Human
Entrez Gene: 20341Mouse
Entrez Gene: 140927Rat
Omim: 604188Human
SwissProt: Q13228Human
SwissProt: P17563Mouse
SwissProt: Q8VIF7Rat
Unigene: 632460Human
Unigene: 16617Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.