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货号： bs-4205R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-4205R-AF350
- 英文名称
- Anti-hnRNP F/AF350
- 中文名称
- AF350标记的异质核糖核蛋白F抗体
- 别 名
- Heterogeneous nuclear ribonucleoprotein F; Heterogeneous nuclear ribonucleoprotein F; hnRNP F; HNRNPF; hnRP F; hnRPF; mcs94 1; MGC110997; Nucleolin like protein; Nucleolin like protein mcs94 1; OK/SW cl.23; Ribonucleoprotein F; HNRPF_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 染色质和核信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 46kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human hnRNP F
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
hnRNP F is part of the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). These are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA) and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. hnRNP F binds to RNAs which have guanosine-rich sequences.
Function:
Component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complexes which provide the substrate for the processing events that pre-mRNAs undergo before becoming functional, translatable mRNAs in the cytoplasm. Plays a role in the regulation of alternative splicing events. Binds G-rich sequences in pre-mRNAs and keeps target RNA in an unfolded state.
Subunit:
Identified in the spliceosome C complex. Interacts with AGO1, AGO2, TBP and TXNL4/DIM1.
Subcellular Location:
Nucleus, nucleoplasm.
Tissue Specificity:
Expressed ubiquitously.
Post-translational modifications:
Sumoylated.
Similarity:
Contains 3 RRM (RNA recognition motif) domains.
Database links:Entrez Gene: 3185 Human
Entrez Gene: 98758 Mouse
Entrez Gene: 64200 Rat
Omim: 601037 Human
SwissProt: Q5E9J1 Cow
SwissProt: P52597 Human
SwissProt: Q9Z2X1 Mouse
SwissProt: Q794E4 Rat
Unigene: 712955 Human
Unigene: 808 Human
Unigene: 422979 Mouse
Unigene: 476420 Mouse
Unigene: 144596 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.