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货号： bs-5823R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5823R-AF350
- 英文名称
- Anti-K Cadherin/AF350
- 中文名称
- AF350标记的钙粘蛋白6抗体
- 别 名
- Cadherin 6; Cadherin6; Cadherin-6; Cadherin 6 type 2; Cadherin fetal kidney; Cadherin6; CDH 6; CDH6; KCAD; Kidney cadherin; CADH6_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 信号转导 细胞粘附分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Cow, Horse,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 82kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human K Cadherin
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
K Cadherin (Cadherin 6) is a type II classical cadherin from the cadherin superfamily. It is a calcium dependent cell-cell adhesion membrane glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins preferentially interact with themselves in a homophilic manner in connecting cells. K Cadherin is highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. It is also expressed in certain liver and kidney carcinomas.
Function:
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
Subcellular Location:
Cell membrane; Single-pass type I membrane protein.
Tissue Specificity:
Highly expressed in brain, cerebellum, and kidney. Lung, pancreas, and gastric mucosa show a weak expression. Also expressed in certain liver and kidney carcinomas.
Similarity:
Contains 5 cadherin domains.
Database links:Entrez Gene: 1004 Human
Entrez Gene: 12563 Mouse
Entrez Gene: 25409 Rat
Omim: 603007 Human
SwissProt: P55285 Human
SwissProt: P97326 Mouse
SwissProt: P55280 Rat
Unigene: 124776 Human
Unigene: 171054 Human
Unigene: 57048 Mouse
Unigene: 10390 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.