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货号： bs-5831R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-5831R-AF350
- 英文名称
- Anti-ANKHD1/AF350
- 中文名称
- AF350标记的艾滋病病毒制约锚定蛋白抗体
- 别 名
- ANKH1_HUMAN; ANKHD 1; ANKHD1; Ankyrin repeat and KH domain containing 1; Ankyrin repeat and KH domain containing protein 1; Ankyrin repeat and KH domain-containing protein 1; HIV-1 Vpr-binding ankyrin repeat protein; HIV1 Vpr binding ankyrin repeat protein; hMASK; MASK; Multiple ankyrin repeats single KH domain; Multiple ankyrin repeats single KH domain homolog; VBARP.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 细菌及病毒 细胞粘附分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 269kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ANKHD1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.
Function:
May play a role as a scaffolding protein that may be associated with the abnormal phenotype of leukemia cells. Isoform 2 may possess an antiapoptotic effect and protect cells during normal cell survival through its regulation of caspases.
Subunit:
Interacts with PTPN11. Isoform 2 interacts with HIV-1 VPR.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Ubiquitous with high expression in cervix, spleen and brain. Expressed in hematopoietic cells with increased expression in leukemia cells. Isoform 2 is highly expressed in spleen with almost no expression in muscle and brain.
Similarity:
Belongs to the mask family.
Contains 25 ANK repeats.
Contains 1 KH domain.
Database links:Entrez Gene: 54882 Human
Omim: 610500 Human
SwissProt: Q8IWZ3 Human
Unigene: 594084 Human
Unigene: 720987 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.