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货号： bs-11892R 基本售价： 1380.0 元 规格： 100ul
- 规格：100ul
- 价格：1380.00元
- 规格：200ul
- 价格：2200.00元
产品信息
- 产品编号
- bs-11892R
- 英文名称
- NAV2
- 中文名称
- 维甲酸诱导神经母细胞瘤蛋白1抗体
- 别 名
- HELAD1; Helicase, APC down regulated 1; KIAA1419; mCG 145366; mKIAA3015; NAV 2; Neuron navigator 2; POMFIL2; Pore membrane and/or filament interacting like protein 2; RAINB1; RAINB2; Retinoic acid inducible in neuroblastoma 1; Steerin 2; STEERIN2; Unc 53 homolog 2; Unc53H2; NAV2_HUMAN.
- 规格价格
- 100ul/1380元购买 200ul/2200元购买 大包装/询价
- 说 明 书
- 100ul 200ul
- 研究领域
- 肿瘤 细胞生物 神经生物学 肿瘤细胞生物标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Dog, Cow, Horse, Rabbit,
- 产品应用
- WB=1:500-2000 ELISA=1:500-1000 IHC-P=1:400-800 IHC-F=1:400-800 ICC=1:100-500 IF=1:100-500 （石蜡切片需做抗原修复）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 268kDa
- 细胞定位
- 细胞核
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human NAV2/RAINB1:21-120/2488
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- PubMed
- PubMed
- 产品介绍
- background:
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Function:
NAV2 protein shows high similarity to Caenorhabditis elegans, unc-53, that is required for axonal elongation of mechanosensory neurons, suggesting that these proteins are orthologs. Thus, NAV2 may be involved in the vitamin A metabolite, atRA (all-trans retinoic acid)-mediated neurite outgrowth. NAV2 possesses 3 to 5 helicase activity and exonuclease activity and is involved in the development of different sensory organs.
Subcellular Location:
Nuclear.
Tissue Specificity:
Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
Similarity:
Belongs to the Nav/unc-53 family.
Contains 1 CH (calponin-homology) domain.
SWISS:
Q8IVL1
Gene ID:
89797
Database links:Entrez Gene: 89797Human
Omim: 607026Human
SwissProt: Q8IVL1Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
- 产品图片
Sample: U251 Cell (Human) Lysate at 30 ug
Primary: Anti- NAV2 (bs-11892R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 268kD
Observed band size: 160kD
Sample: HepG2 Cell (Human) Lysate at 30 ug
Primary: Anti- NAV2 (bs-11892R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 268kD
Observed band size: 160kD