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货号： bs-6073R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6073R-AF350
- 英文名称
- Anti-MFSD2A/AF350
- 中文名称
- AF350标记的促进调解蛋白家族2A抗体
- 别 名
- Major facilitator superfamily domain containing 2; Major facilitator superfamily domain containing 2A; Major facilitator superfamily domain-containing protein 2A; MFS2A_HUMAN; MFSD2; MFSD2A.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 神经生物学 信号转导 转录调节因子 G蛋白偶联受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human MFSD2A
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
MFSD2 is a 543 amino acid multi-pass membrane protein of the endoplasmic reticulum that is involved in beta-adrenergic signaling during thermogenesis. Existing as three alternatively spliced isoforms, MFSD2 plays a role in G1 regulation and is encoded by a gene that maps to human chromosome 1p34.2. Human chromosome 1 spans 260 million base pairs, contains over 3,000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome.
Function:
Play a role in thermogenesis via beta-adrenergic signaling pathway.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Similarity:
Belongs to the major facilitator superfamily.
Database links:Entrez Gene: 84879 Human
Entrez Gene: 76574 Mouse
Entrez Gene: 298504 Rat
Omim: 614397 Human
SwissProt: Q8NA29 Human
SwissProt: Q9DA75 Mouse
Unigene: 655177 Human
Unigene: 331842 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.