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货号： bs-6198R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6198R-AF350
- 英文名称
- Anti-TROP2/AF350
- 中文名称
- AF350标记的细胞表面糖蛋白Trop2抗体（胰腺癌标志物蛋白）
- 别 名
- Cell surface glycoprotein Trop 2; Cell surface glycoprotein Trop-2; Cell surface glycoprotein Trop2; Epithelial glycoprotein 1; GA733 1; GA7331; M1S 1; M1S1; Membrane component chromosome 1 surface marker 1; Pancreatic carcinoma marker protein GA733 1; Pancreatic carcinoma marker protein GA733-1; Pancreatic carcinoma marker protein GA7331; TACD 2; TACD2_HUMAN; TACSTD 2; TACSTD2; Trop 2; Trop2; Tumor associated calcium signal transducer 2 precursor; Tumor-associated calcium signal transducer 2.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 信号转导 肿瘤细胞生物标志物
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 33kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TROP2/TACD2
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]
Function:
May function as a growth factor receptor.
Subcellular Location:
Membrane; Single-pass type I membrane protein.
Tissue Specificity:
Placenta, pancreatic carcinoma cell lines.
Post-translational modifications:
The N-terminus is blocked.
DISEASE:
Corneal dystrophy, gelatinous drop-like (GDLD) [MIM:204870]: A form of lattice corneal dystrophy, a class of inherited stromal amyloidoses characterized by pathognomonic branching lattice figures in the cornea. GDLD is an autosomal recessive disorder characterized by severe corneal amyloidosis leading to blindness. Clinical manifestations, which appear in the first decade of life, include blurred vision, photophobia, and foreign-body sensation. By the third decade, raised, yellowish-gray, gelatinous masses severely impair visual acuity. Note=The disease is caused by mutations affecting the gene represented in this entry.
Similarity:
Belongs to the EPCAM family.
Contains 1 thyroglobulin type-1 domain.
Database links:Entrez Gene: 4070Human
Entrez Gene: 56753Mouse
Entrez Gene: 494343Rat
Omim: 137290Human
SwissProt: P09758Human
SwissProt: Q8BGV3Mouse
SwissProt: Q6P9Z6Rat
Unigene: 23582Human
Unigene: 439913Mouse
Unigene: 24809Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.