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货号： bs-6295R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6295R-AF350
- 英文名称
- Anti-Oncostatin M/AF350
- 中文名称
- AF350标记的癌基因蛋白抑瘤素M抗体
- 别 名
- ONCM_HUMAN; Oncostatin M; Oncostatin M precursor; Oncostatin-M; OSM.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 心血管 细胞生物 免疫学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 26kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Oncostatin M (181-225)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor.
Function:
Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity).
Subcellular Location:
Secreted.
Similarity:
Belongs to the LIF/OSM family.
Database links:Entrez Gene: 5008 Human
Entrez Gene: 18413 Mouse
Entrez Gene: 289747 Rat
Omim: 165095 Human
SwissProt: P13725 Human
SwissProt: P53347 Mouse
SwissProt: Q65Z15 Rat
Unigene: 248156 Human
Unigene: 131422 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
Oncostatin M抑瘤素M。OSM和LIF，G-CSF，IL-6 ，CNTF同属于一组细胞因子，是一种调节生长的细胞因子。能抑制某些肿瘤细胞的生长，但不影响正常细胞。由巨噬细胞和活化T淋巴细胞分泌。