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货号： bs-6613R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6613R-AF350
- 英文名称
- Anti-BCAT1/AF350
- 中文名称
- AF350标记的胞浆支链氨基酸酸转氨酶抗体
- 别 名
- cytosolic; BCAT; BCAT(c); Bcat1; BCAT1_HUMAN; BCT1; Branched chain amino acid aminotransferase, cytosolic; Branched-chain-amino-acid aminotransferase; ECA39; MECA39; PNAS 121; Protein ECA39.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BCAT1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes the cytosolic form of the enzyme branched-chain amino acid transaminase. This enzyme catalyzes the reversible transamination of branched-chain alpha-keto acids to branched-chain L-amino acids essential for cell growth. Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia. As there is also a gene encoding a mitochondrial form of this enzyme, mutations in either gene may contribute to these disorders. Alternatively spliced transcript variants have been described. [provided by RefSeq, May 2010].
Function:
Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.
Subunit:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
During embryogenesis, expressed in the brain and kidney. Overexpressed in MYC-induced tumors such as Burkitts lymphoma.
Similarity:
Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
Database links:Entrez Gene: 586Human
Entrez Gene: 12035Mouse
Omim: 113520Human
SwissProt: P54687Human
SwissProt: P24288Mouse
Unigene: 438993Human
Unigene: 4606Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.