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货号： bs-6673R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6673R-AF350
- 英文名称
- Anti-GIRK3/AF350
- 中文名称
- AF350标记的G蛋白激活内向钾通道3抗体
- 别 名
- G protein activated inward rectifier potassium channel 3; G protein coupled inward rectifier potassium channel; G protein-activated inward rectifier potassium channel 3; GIRK-3; GIRK3; Inward rectifier K(+) channel Kir3.3; Inwardly rectifier K(+) channel Kir3.3; Inwardly rectifier K+ channel KIR3.3; inwardly rectifying subfamily J member 9; IRK9_HUMAN; Kcnj9; KIR3.3; Potassium channel; Potassium channel inwardly rectifying subfamily J member 9; Potassium inwardly rectifying channel subfamily J member 9; Potassium inwardly rectifying channel subfamily J9.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 心血管 细胞生物 神经生物学 信号转导 通道蛋白 G蛋白偶联受体 细胞表面分子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 43kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GIRK3/KCNJ9
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
KCNJ9 belongs to the inward rectifier-type potassium channel family and is controlled by G proteins. It associates with another G-protein-activated potassium channel to form a heteromultimeric pore-forming complex. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Function:
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Subunit:
Associates with GIRK1 to form a G-protein-activated heteromultimer pore-forming unit
Subcellular Location:
Membrane; Multi-pass membrane protein.
Similarity:
Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ9 subfamily.
Database links:
UniProtKB/Swiss-Prot: Q92806.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.