产品中心
当前位置：首页>产品中心Anti-TFDP3/AF350
货号： bs-6400R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6400R-AF350
- 英文名称
- Anti-TFDP3/AF350
- 中文名称
- AF350标记的转录因子DP3/肝癌相关抗原661抗体
- 别 名
- Cancer/testis antigen 30; CT30; E2F-like; HCA661; Hepatocellular carcinoma-associated antigen 661; TFDP3; Transcription factor Dp family member 3; TFDP3_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞周期蛋白 转录调节因子 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 45kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TFDP3
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the DP family of transcription factors. These factors heterodimerize with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes. This protein functions as a negative regulator and inhibits the DNA binding and transcriptional activities of E2F factors.
Function:
Competitive inhibitor of E2F-mediated transactivation activity. Impairs E2F-mediated cell-cycle progression from G(1) to S phase.
Subunit:
Heterodimer: with E2F family members. TFDP3/E2F heterodimers do not bind DNA and repress E2F-dependent transcriptional activity.
Subcellular Location:
Nucleus. Cytoplasm. Note=Translocates to the nucleus on heterodimerization with E2F family members.
Tissue Specificity:
Predominantly expressed in testis. Low level of expression in pancreas. Highly expressed in ovarian and colon cancer cell lines.
Similarity:
Belongs to the E2F/DP family.
Database links:Entrez Gene: 51270 Human
SwissProt: Q5H9I0 Human
Unigene: 142908 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.