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货号： bs-7973R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-7973R-AF350
- 英文名称
- Anti-ATE1/AF350
- 中文名称
- AF350标记的精氨酸tRNA的蛋白转移酶1抗体
- 别 名
- Arginine tRNA protein transferase 1; Arginyl-tRNA--protein transferase 1; Arginyl-tRNA-protein transferase; Arginyltransferase 1; R transferase 1; EC 2.3.2.8; AI225793; ATE1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 59kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human ATE1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
ATE1, also known as arginyltransferase 1, is an enzyme that is involved in the post-translational conjugation of arginine to the N-terminal aspartate or glutamate of a protein. This arginylation is required for degradation of the protein via the ubiquitin pathway. There are two named isoforms.
Function:
Involved in the post-translational conjugation ofarginine to the N-terminal aspartate or glutamate of a protein.This arginylation is required for degradation of the protein viathe ubiquitin pathway. Does not arginylate cysteine residues (Bysimilarity).
Subunit:
Monomer (Potential).
Subcellular Location:
Isoform ATE1-1: Nucleus (By similarity).Cytoplasm (By similarity).
Isoform ATE1-2: Cytoplasm (By similarity).
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the R-transferase family.
Database links:
UniProtKB/Swiss-Prot: O95260.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.