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货号： bs-6424R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-6424R-AF350
- 英文名称
- Anti-SNX27/AF350
- 中文名称
- AF350标记的SNX27蛋白抗体
- 别 名
- Methamphetamine responsive transcript 1; MGC126871; MGC126873; MGC20471; MRT1; MY014; RP11-98D18.12; Sorting nexin family member 27; KIAA0488; SNX27_HUMAN; Sorting nexin-27.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 信号转导
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 60kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human SNX27
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
SNX27 is involved in endocytic trafficking. In T lymphocytes it participates in the endocytic recycling pathway. SNX27 recruits PSCDBP and HT4R to early endosomes.
Function:
Involved in endocytic trafficking (By similarity). In T lymphocytes, participates in endocytic recycling pathway. Recruits PSCDBP and HT4R to early endosomes (By similarity).
Subunit:
Interacts with PSCDBP. Isoforms 1 and 2 directly interact with DGKZ. Isoforms 1 and 2 interact with HT4R isoform 5-HTA(A). Interacts with MCC.
Subcellular Location:
Cytoplasm, cytosol. Early endosome. Note=In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
Tissue Specificity:
Expressed in cells of hematopoietic origin (at protein level).
Similarity:
Belongs to the sorting nexin family.
Contains 1 PDZ (DHR) domain.
Contains 1 PX (phox homology) domain.
Contains 1 Ras-associating domain.
Database links:Entrez Gene: 81609 Human
Omim: 611541 Human
SwissProt: Q96L92 Human
Unigene: 192326 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.