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货号： bs-8158R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8158R-AF350
- 英文名称
- Anti-HCV NS5A transactivated protein 8/AF350
- 中文名称
- AF350标记的丙肝病毒NS5A反转录蛋白8抗体
- 别 名
- BTB (POZ) domain containing 1; BTB domain containing 1; BTB/POZ domain containing protein 1; BTBD 1; C15orf1; HCV NS5A transactivated protein 8; Hepatitis C virus NS5A transactivated protein 8; NS5ATP8; BTBD1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 细胞周期蛋白 转录调节因子 细菌及病毒 细胞分化
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 53kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human BTBD1/HCV NS5A transactivated protein 8
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
BTBD1 contains a proline-rich region and a BTB/POZ domain which are typically involved in protein-protein interactions. The C-terminus of BTBD1 binds topoisomerase I and BTBD1 also interacts with TRIM5 isoform Delta. BTBD1 localizes to cytoplasmic bodies and is essential for myogenic differentiation.
Function:
Probable substrate-specific adapter of an E3ubiquitin-protein ligase complex which mediates the ubiquitinationand subsequent proteasomal degradation of target proteins.
Subunit:
Interacts with topoisomerase 1 and with TRIM5 isoformDelta. Interacts with CUL3.
Subcellular Location:
Cytoplasm, P-body. Note=Cytoplasmic bodies.
Tissue Specificity:
Ubiquitous; higher levels in heart andskeletal muscle.
Similarity:
Contains 1 BTB (POZ) domain.
Database links:
UniProtKB/Swiss-Prot: Q9H0C5.1
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.