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货号： bs-8274R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-8274R-AF350
- 英文名称
- Anti-GIMAP8/AF350
- 中文名称
- AF350标记的GTP酶IMAP家族成员8抗体
- 别 名
- GTPase IMAP family member 8; hIAN6; Human immune associated nucleotide 6; IAN9; IANT; Immune associated nucleotide; Immune-associated nucleotide-binding protein 9; Protein IanT; GIMA8_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 G蛋白信号
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Horse, Rabbit,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 75kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GIMAP8
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The GTPase of the immunity-associated protein (GIMAP) family of proteins include seven members that are expressed by genes residing on human chromosome 7. GIMAP proteins have been implicated in the regulation of lymphomyeloid cell survival. GIMAP8, also known as IAN9 (immune-associated nucleotide-binding protein 9) or IANT, is a 665 amino acid protein that localizes to Golgi apparatus, Endoplasmic reticulum and mitochondria. Suggested to have an anti-apoptotic effect on the immune system, GIMAP8 plays a role in infection response and is encoded by a gene that maps to human chromosome 7q36.1. Chromosome 7 houses over 1,000 genes, comprises nearly 5% of the human genome and has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome.
Function:
Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections (By similarity).
Subcellular Location:
Endoplasmic reticulum (By similarity). Golgi apparatus (By similarity). Mitochondrion (By similarity).
Similarity:
Belongs to the IAN GTP-binding protein family.
Database links:
UniProtKB/Swiss-Prot: Q8ND71.2
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.