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货号： bs-9312R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9312R-AF350
- 英文名称
- Anti-C21orf106/DIP2A/AF350
- 中文名称
- AF350标记的21号染色体开放阅读框106抗体
- 别 名
- C21orf106; DIP 2A; DIP2; DIP2 disco interacting protein 2 homolog A; DIP2 homolog A; DIP2A; DIP2 like protein; Disco interacting protein 2 homolog; KIAA0184; DIP2A_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 细胞周期蛋白 转录调节因子 细胞分化 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Cow, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 170kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human DIP2A/C21orf106
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
DIP2A, also known as DIP2, is a 1571 amino acid nuclear protein. It is one of three human homologs (DIP2A, DIP2B and DIP2C) of the Drosophila dip2 (disconnected-interacting protein 2) protein. In Drosophila, dip2 interacts with disco, a protein required for neuronal connections in the visual systems of larvae and adults. The closest vertebrate homologs to disco are the basonuclin genes. In mice, DIP2 homologs show restricted expression to the brain. This suggests that, similar to the function of Drosophila dip2, vertebrate DIP2 homologs may play a role in the development of the nervous system. Expressed ubiquitously with highest expression in the brain, DIP2A is thought to function in signaling throughout the central nervous system by providing positional clues for axon patterning and pathfinding. Four isoforms of DIP2A exist due to alternative splicing events.
Function:
May provide positional cues for axon pathfinding and patterning in the central nervous system.
Subcellular Location:
Nuclear
Tissue Specificity:
Low expression in all tissues tested.
Similarity:
Belongs to the DIP2 family.
Database links:Entrez Gene: 23181 Human
Entrez Gene: 64451 Mouse
Omim: 607711 Human
SwissProt: Q14689 Human
SwissProt: Q8BWT5 Mouse
Unigene: 189585 Human
Unigene: 33183 Mouse
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.