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货号： bs-9878R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9878R-AF350
- 英文名称
- Anti-Cyclophilin 40/PPID/AF350
- 中文名称
- AF350标记的亲环蛋白（亲环素）40抗体
- 别 名
- 40 kDa peptidyl prolyl cis trans isomerase; 40 kDa peptidyl prolyl cis trans isomerase D; 40 kDa peptidyl-prolyl cis-trans isomerase; Cyclophilin D; Cyclophilin D; Cyclophilin related protein; Cyclophilin-40; Cyclophilin-related protein; Cyclophilin40; CyclophilinD; CYP 40; CYP 40; CYP-40; CYP40; CYP40; CYPD; CYPD; MGC33096; Peptidyl Prolyl Isomerase D; Peptidyl Prolyl Isomerase D; Peptidyl-prolyl cis-trans isomerase D; Peptidylprolyl isomerase D; PPIase; PPIase D; PPID; PPID; PPID_HUMAN; Rotamase; Rotamase D.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 转录调节因子 转运蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Cow, Horse, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 20, 40kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from hu Cyclophilin D
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Cyclophilins are conserved, ubiquitous and abundant cytosolic peptidyl-prolyl cis-trans isomerases that accelerate the isomerization of XaaPro peptide bonds and the refolding of proteins. Human cyclophilin A (CyPA), an intracellular protein of 165 amino acids, is the target of cyclosporin A (CsA) and is encoded by a single unique gene conserved from yeast to humans. Cyclophilin B (CyPB) is secreted in biological fluids such as blood or milk and binds to a specific receptor present on the human lymphoblastic cell line Jurkat and on human peripheral blood lymphocytes. Cyclophilin D (CyP40) is a widely expressed cytoplasmic protein that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. It is a widely expressed cytoplasmic protein.
Function:
PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.
Subunit:
Binds ESR1.
Subcellular Location:
Cytoplasm.
Tissue Specificity:
Widely expressed.
Similarity:
Belongs to the cyclophilin-type PPIase family. PPIase D subfamily.
Contains 1 PPIase cyclophilin-type domain.
Contains 3 TPR repeats.
Database links:Entrez Gene: 5481 Human
Entrez Gene: 67738 Mouse
Entrez Gene: 361967 Rat
Omim: 601753 Human
SwissProt: Q08752 Human
SwissProt: Q9CR16 Mouse
SwissProt: Q6DGG0 Rat
Unigene: 183958 Human
Unigene: 295252 Mouse
Unigene: 136915 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.