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货号： bs-9934R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-9934R-AF350
- 英文名称
- Anti-C11ORF77/AF350
- 中文名称
- AF350标记的11号染色体开放阅读框77抗体
- 别 名
- Chromosome 11 open reading frame 77; FLJ32675; HARB1_HUMAN; HARBI1; Harbinger transposase derived 1; Harbinger transposase-derived nuclease; Putative nuclease HARBI1.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 免疫学 神经生物学 细胞周期蛋白
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep,
- 产品应用
- IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 39kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human C11ORF77/HARBI1
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
HARBI1 is a 349 amino acid nuclear and cytoplasmic protein belonging to the HARBI1 family. Members of the HARBI1 family of proteins are highly conserved in humans to various bony fish. Considered a transposase-derived protein, HARBI1 may possess nuclease activity and is expressed in brain, eye, nerve tissue, kidney and lung. HARBI1 utilizes divalent metal cations as cofactors, interacts with NAIF1 and promotes translocation to the nucleus. HARBI1 is encoded by a gene located on human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Function:
Transposase-derived protein that may have nuclease activity (Potential). Does not have transposase activity.
Subunit:
Interacts with NAIF1.
Subcellular Location:
Nucleus. Cytoplasm. Interaction with NAIF1 promotes translocation to the nucleus.
Tissue Specificity:
Detected in brain, eye, nerve tissue, kidney and lung.
Similarity:
Belongs to the HARBI1 family.
Database links:Entrez Gene: 283254 Human
Entrez Gene: 241547 Mouse
Entrez Gene: 690164 Rat
SwissProt: Q96MB7 Human
SwissProt: Q8BR93 Mouse
SwissProt: B0BN95 Rat
Unigene: 714463 Human
Unigene: 130331 Mouse
Unigene: 198635 Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.