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货号： bs-11439R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11439R-AF350
- 英文名称
- Anti-TXNDC11/AF350
- 中文名称
- AF350标记的硫氧还蛋白11抗体
- 别 名
- EF-hand-binding protein 1; EFP1; RGD1307538; Thioredoxin domain-containing protein 11; TXD11_HUMAN; TXNDC11; 2810408E11Rik; AI427833.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 肿瘤 细胞生物 信号转导 转录调节因子
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Dog, Cow, Horse, Sheep,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 110kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human TXNDC11
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
Function:
May act as a redox regulator involved in DUOX proteins folding. The interaction with DUOX1 and DUOX2 suggest that it belongs to a multiprotein complex constituting the thyroid H(2)O(2) generating system. It is however not sufficient to assist DUOX1 and DUOX2 in H(2)O(2) generation.
Subunit:
Interacts with the cytoplasmic part of DUOX1 and DUOX2. Interacts with TPO and CYBA.
Subcellular Location:
Endoplasmic reticulum membrane.
Tissue Specificity:
Widely expressed at low level. Expressed at higher level in thyroid and prostate.
Similarity:
Belongs to the protein disulfide isomerase family.
Contains 2 thioredoxin domains.
Database links:Entrez Gene: 490003 Dog
Entrez Gene: 100056118 Horse
Entrez Gene: 51061 Human
SwissProt: Q6PKC3 Human
Unigene: 313847 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.