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货号： bs-11678R-AF350 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-11678R-AF350
- 英文名称
- Anti-Nuclear Pore Complex Proteins/Nup107/AF350
- 中文名称
- AF350标记的核孔复合体蛋白抗体
- 别 名
- 107 kDa nucleoporin; NPC proteins; NU107_HUMAN; Nuclear pore complex protein Nup107; Nucleoporin 107kDa; Nucleoporin Nup107; NUP 107; NUP 84; NUP107; NUP153; NUP155; NUP84; NUP98.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 染色质和核信号 神经生物学 表观遗传学
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- Human, Mouse, Rat, Pig, Horse, Rabbit,
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 106kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 1mg/ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human Nuclear Pore Complex Proteins (501-600aa)
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
This gene encodes a member of the nucleoporin family. The protein is localized to the nuclear rim and is an essential component of the nuclear pore complex (NPC). All molecules entering or leaving the nucleus either diffuse through or are actively transported by the NPC. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008]
Function:
Essential component of nuclear pore complex. Required for the assembly of peripheral proteins into the nuclear pore complex.
Subunit:
Forms part of the Nup160 subcomplex in the nuclear pore which is composed of Nup160, Nup133, Nup107 and Nup96. This complex plays a role in RNA export and in tethering Nup98 and Nup153 to the nucleus.
Subcellular Location:
Nucleus, nuclear pore complex. Chromosome, centromere, kinetochore. Note=Located on both the cytoplasmic and nuclear sides of the nuclear pore. During mitosis, localizes to the kinetochores.
Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.
Similarity:
Belongs to the nucleoporin Nup84/Nup107 family.
Database links:Entrez Gene: 57122Human
Entrez Gene: 103468Mouse
Entrez Gene: 116555Rat
Omim: 607617Human
SwissProt: P57740Human
SwissProt: Q3TT06Mouse
SwissProt: Q3V395Mouse
SwissProt: Q569X8Mouse
SwissProt: Q8BH74Mouse
SwissProt: P52590Rat
Unigene: 524574Human
Unigene: 12568Mouse
Unigene: 11398Rat
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.