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货号： bsm-30074M-FITC-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bsm-30074M-FITC-APC
- 英文名称
- Anti-human CD14-FITC/APC
- 中文名称
- APC标记的FITC标记小鼠抗人CD14单克隆抗体
- 别 名
- CD14 antigen; CD14 molecule; Lipopolysaccharide receptor; LPSR; Monocyte Differentiation Antigen 14; Monocyte differentiation antigen CD14; Myeloid cell specific leucine rich glycoprotein; CD14_MOUSE; Myeloid cell-specific leucine-rich glycoprotein.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 细胞生物 免疫学 干细胞 细胞表面分子 细胞类型标志物 淋巴细胞
- 抗体来源
- Mouse
- 克隆类型
- Monoclonal
- 交叉反应
- Human,
- 产品应用
- Flow-Cyt=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 35/40kDa
- 性 状
- Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein G
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010]
Function:
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Subunit:
Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.
Subcellular Location:
Cell membrane; Lipid-anchor, GPI-anchor.
Similarity:
Contains 11 LRR (leucine-rich) repeats.
Database links:Entrez Gene: 929 Human
Omim: 158120 Human
SwissProt: P08571 Human
Unigene: 163867 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.