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货号： bs-10703R-APC 基本售价： 2980.0 元 规格： 100ul
产品信息
- 产品编号
- bs-10703R-APC
- 英文名称
- Anti-GRINA/APC
- 中文名称
- APC标记的谷氨酸受体相关蛋白1抗体
- 别 名
- Glutamate [NMDA] receptor associated protein 1; Glutamate receptor, ionotropic, N methyl D aspartate associated protein 1 (glutamate binding); Glutamate receptor, NMDA subtype, glutamate binding subunit; HNRGW; LFG1; MGC99687; NMDA receptor glutamate binding subunit; NMDARA1; Putative MAPK activating protein PM02; TMBIM3; Transmembrane BAX inhibitor motif containing 3; LFG1_HUMAN.
- 规格价格
- 100ul/2980元购买 大包装/询价
- 说 明 书
- 100ul
- 研究领域
- 神经生物学 通道蛋白 细胞膜受体
- 抗体来源
- Rabbit
- 克隆类型
- Polyclonal
- 交叉反应
- 产品应用
- ICC=1:50-200 IF=1:50-200
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
- 分 子 量
- 41kDa
- 性 状
- Lyophilized or Liquid
- 浓 度
- 2mg/1ml
- 免 疫 原
- KLH conjugated synthetic peptide derived from human GRINA
- 亚 型
- IgG
- 纯化方法
- affinity purified by Protein A
- 储 存 液
- Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.05M PB, pH 7.5.
- 保存条件
- Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
- 产品介绍
- background:
Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration. Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, cation-specific ion channels. Synaptic and extrasynaptic NMDA receptors have been shown to have opposite effects on neuronal survival, CREB function and gene regulation. As one of the four major proteins of the NMDA receptor ion channel, GRINA (Glutamate [NMDA] receptor-associated protein 1), also designated NMDA receptor glutamate-binding subunit or putative MAPK-activating protein PM02, is a 371 amino acid multi-pass transmembrane protein. Due to the chromosomal location of the gene encoding GRINA, studies have linked possible GRINA involvement with a form of idiopathic generalized epilepsy.
Function:
Potential apoptotic regulator.
Subcellular Location:
Membrane; Multi-pass membrane protein (potential).
Similarity:
Belongs to the BI1 family. LFG subfamily.
Database links:Entrez Gene: 2907 Human
Omim: 138251 Human
SwissProt: Q7Z429 Human
Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.